Synthesis of (18)F-Tetrafluoroborate via Radiofluorination of Boron Trifluoride and Evaluation in a Murine C6-Glioma Tumor Model

The sodium/iodide symporter (NIS) is under investigation as a reporter for noninvasive imaging of gene expression. Although (18)F-tetrafluoroborate ((18)F-TFB, (18)F-BF(4)(−)) has shown promise as a PET imaging probe for NIS, the current synthesis method using isotopic exchange gives suboptimal radi...

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Dettagli Bibliografici
Pubblicato in:J Nucl Med
Autori principali: Jiang, Huailei, Bansal, Aditya, Pandey, Mukesh K., Peng, Kah-Whye, Suksanpaisan, Lukkana, Russell, Stephen J., DeGrado, Timothy R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society of Nuclear Medicine 2016
Soggetti:
Basic Science Investigations
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5695578/
https://ncbi.nlm.nih.gov/pubmed/27103021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.115.170894
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