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Enhanced noninvasive imaging of oncology models using the NIS reporter gene and bioluminescence imaging

Noninvasive bioluminescence imaging (BLI) of luciferase-expressing tumor cells has advanced pre-clinical evaluation of cancer therapies. Yet despite its successes, BLI is limited by poor spatial resolution and signal penetration, making it unusable for deep tissue or large animal imaging and prevent...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Cancer Gene Ther
Hauptverfasser: Vandergaast, Rianna, Khongwichit, Sarawut, Jiang, Huailei, DeGrado, Timothy R., Peng, Kah-Whye, Smith, Duncan R., Russell, Stephen J., Suksanpaisan, Lukkana
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group US 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7170803/
https://ncbi.nlm.nih.gov/pubmed/30674994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41417-019-0081-2
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