Autogenous cross-regulation of Quaking mRNA processing and translation balances Quaking functions in splicing and translation

Quaking protein isoforms arise from a single Quaking gene and bind the same RNA motif to regulate splicing, translation, decay, and localization of a large set of RNAs. However, the mechanisms by which Quaking expression is controlled to ensure that appropriate amounts of each isoform are available...

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Foilsithe in:Genes Dev
Main Authors: Fagg, W. Samuel, Liu, Naiyou, Fair, Jeffrey Haskell, Shiue, Lily, Katzman, Sol, Donohue, John Paul, Ares, Manuel
Formáid: Artigo
Teanga:Inglês
Foilsithe: Cold Spring Harbor Laboratory Press 2017
Ábhair:
Research Paper
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5695090/
https://ncbi.nlm.nih.gov/pubmed/29021242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.302059.117
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