Autogenous cross-regulation of Quaking mRNA processing and translation balances Quaking functions in splicing and translation

Quaking protein isoforms arise from a single Quaking gene and bind the same RNA motif to regulate splicing, translation, decay, and localization of a large set of RNAs. However, the mechanisms by which Quaking expression is controlled to ensure that appropriate amounts of each isoform are available...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Genes Dev
Prif Awduron: Fagg, W. Samuel, Liu, Naiyou, Fair, Jeffrey Haskell, Shiue, Lily, Katzman, Sol, Donohue, John Paul, Ares, Manuel
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Cold Spring Harbor Laboratory Press 2017
Pynciau:
Research Paper
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5695090/
https://ncbi.nlm.nih.gov/pubmed/29021242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.302059.117
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