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Discovery of Tamoxifen and N-Desmethyl Tamoxifen Protein Targets in MCF-7 Cells Using Large-Scale Protein Folding and Stability Measurements

The proteins in an MCF-7 cell line were probed for tamoxifen (TAM) and n-desmethyl tamoxifen (NDT) induced stability changes using the Stability of Proteins from Rates of Oxidation (SPROX) technique in combination with two different quantitative proteomics strategies, including one based on SILAC an...

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Pubblicato in:J Proteome Res
Autori principali: Ogburn, Ryenne N., Jin, Lorrain, Meng, He, Fitzgerald, Michael C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5695045/
https://ncbi.nlm.nih.gov/pubmed/28927269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jproteome.7b00442
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