Notch1 confers a resistance to glucocorticoid-induced apoptosis on developing thymocytes by down-regulating SRG3 expression

We previously have reported that SRG3 is required for glucocorticoid (GC)-induced apoptosis in the S49.1 thymoma cell line. Activation of Notch1 was shown to induce GC resistance in thymocytes. However, the specific downstream target of Notch1 that confers GC resistance on thymocytes is currently un...

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Autors principals: Choi, Young I., Jeon, Sung H., Jang, Jiho, Han, Sunmi, Kim, Joong K., Chung, Heekyoung, Lee, Han W., Chung, Hee-Y., Park, Sang D., Seong, Rho H.
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 2001
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC56950/
https://ncbi.nlm.nih.gov/pubmed/11504912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.181076198
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