Adrenomedullin Contributes to Age-Related Memory Loss in Mice and Is Elevated in Aging Human Brains

Memory decline is common in elderly individuals and is the hallmark of Alzheimer’s disease (AD). Memory failure follows the loss of synaptic contacts in the cerebral cortex and hippocampus, caused in part by cytoskeleton disruption. Adrenomedullin (AM) and its gene-related peptide, proadrenomedullin...

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Publicat a:Front Mol Neurosci
Autors principals: Larrayoz, Ignacio M., Ferrero, Hilda, Martisova, Eva, Gil-Bea, Francisco J., Ramírez, María J., Martínez, Alfredo
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2017
Matèries:
Neuroscience
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5694777/
https://ncbi.nlm.nih.gov/pubmed/29187812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2017.00384
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