Adrenomedullin Contributes to Age-Related Memory Loss in Mice and Is Elevated in Aging Human Brains

Memory decline is common in elderly individuals and is the hallmark of Alzheimer’s disease (AD). Memory failure follows the loss of synaptic contacts in the cerebral cortex and hippocampus, caused in part by cytoskeleton disruption. Adrenomedullin (AM) and its gene-related peptide, proadrenomedullin...

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Detalhes bibliográficos
Publicado no:Front Mol Neurosci
Main Authors: Larrayoz, Ignacio M., Ferrero, Hilda, Martisova, Eva, Gil-Bea, Francisco J., Ramírez, María J., Martínez, Alfredo
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5694777/
https://ncbi.nlm.nih.gov/pubmed/29187812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2017.00384
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