PARP-1 Variant Rs1136410 Confers Protection against Coronary Artery Disease in a Chinese Han Population: A Two-Stage Case-Control Study Involving 5643 Subjects

Inhibition of poly(ADP-ribose) polymerase (PARP) may protect against coronary artery disease (CAD) in animal models, and rs1136410, a non-synonymous single nucleotide polymorphism (SNP) in PARP-1, has a potential impact on PARP activities in vitro. This two-stage case-control study, involving 2803 C...

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Detalhes bibliográficos
Publicado no:Front Physiol
Main Authors: Wang, Xue-bin, Cui, Ning-hua, Zhang, Shuai, Guo, Shu-ren, Liu, Ze-jin, Ming, Liang
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Physiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5694467/
https://ncbi.nlm.nih.gov/pubmed/29184509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2017.00916
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