Contributions of PARP‐1 rs1136410 C>T polymorphism to the development of cancer

Poly(ADP‐ribose) polymerase‐1 (PARP‐1) is a nuclear chromatin‐associated enzyme involved in the DNA damage response. SNP rs1136410 C>T, the most studied polymorphism in PARP‐1 gene, is highly implicated in the susceptibility of cancer. However, the roles of PARP‐1 rs1136410 C>T on cancer risk...

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Udgivet i:J Cell Mol Med
Main Authors: Li, Hunian, Zha, Yongjiu, Du, Fang, Liu, Jie, Li, Xiaoquan, Zhao, Xu
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2020
Fag:
Short Communications
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7753995/
https://ncbi.nlm.nih.gov/pubmed/33108038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.16027
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