Bid-Induced Release of AIF/EndoG from Mitochondria Causes Apoptosis of Macrophages during Infection with Leptospira interrogans

Leptospirosis is a global zoonotic infectious disease caused by pathogenic Leptospira species. Leptospire-induced macrophage apoptosis through the Fas/FasL-caspase-8/3 pathway plays an important role in the survival and proliferation of the pathogen in hosts. Although, the release of mitochondrial a...

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Bibliographische Detailangaben
Veröffentlicht in:Front Cell Infect Microbiol
Hauptverfasser: Hu, Wei-Lin, Dong, Hai-Yan, Li, Yang, Ojcius, David M., Li, Shi-Jun, Yan, Jie
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2017
Schlagworte:
Microbiology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5694448/
https://ncbi.nlm.nih.gov/pubmed/29184851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2017.00471
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