Ketamine’s antidepressant effect is mediated by energy metabolism and antioxidant defense system

Fewer than 50% of all patients with major depressive disorder (MDD) treated with currently available antidepressants (ADs) show full remission. Moreover, about one third of the patients suffering from MDD does not respond to conventional ADs and develop treatment-resistant depression (TRD). Ketamine...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Weckmann, Katja, Deery, Michael J., Howard, Julie A., Feret, Renata, Asara, John M., Dethloff, Frederik, Filiou, Michaela D., Iannace, Jamie, Labermaier, Christiana, Maccarrone, Giuseppina, Webhofer, Christian, Teplytska, Larysa, Lilley, Kathryn, Müller, Marianne B., Turck, Christoph W.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5694011/
https://ncbi.nlm.nih.gov/pubmed/29150633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-16183-x
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