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PTK6 regulates growth and survival of endocrine therapy-resistant ER+ breast cancer cells
The non-receptor tyrosine kinase, PTK6/BRK, is highly expressed in multiple tumor types, including prostate, ovarian, and breast cancers, and regulates oncogenic phenotypes such as proliferation, migration, and survival. PTK6 inhibition also overcomes targeted therapy resistance of HER2+ breast canc...
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| Pubblicato in: | NPJ Breast Cancer |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group UK
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5694002/ https://ncbi.nlm.nih.gov/pubmed/29167821 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41523-017-0047-1 |
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