Alarmin S100A8 Activates Alveolar Epithelial Cells in the Context of Acute Lung Injury in a TLR4-Dependent Manner

Alveolar epithelial cells (AECs) are an essential part of the respiratory barrier in lungs for gas exchange and protection against pathogens. Damage to AECs occurs during lung injury and PAMPs/DAMPs have been shown to activate AECs. However, their interplay as well as the mechanism of AECs’ activati...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Chakraborty, Deblina, Zenker, Stefanie, Rossaint, Jan, Hölscher, Anna, Pohlen, Michele, Zarbock, Alexander, Roth, Johannes, Vogl, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5693860/
https://ncbi.nlm.nih.gov/pubmed/29180999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.01493
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