Alarmin S100A8 Activates Alveolar Epithelial Cells in the Context of Acute Lung Injury in a TLR4-Dependent Manner

Alveolar epithelial cells (AECs) are an essential part of the respiratory barrier in lungs for gas exchange and protection against pathogens. Damage to AECs occurs during lung injury and PAMPs/DAMPs have been shown to activate AECs. However, their interplay as well as the mechanism of AECs’ activati...

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Publicat a:Front Immunol
Autors principals: Chakraborty, Deblina, Zenker, Stefanie, Rossaint, Jan, Hölscher, Anna, Pohlen, Michele, Zarbock, Alexander, Roth, Johannes, Vogl, Thomas
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2017
Matèries:
Immunology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5693860/
https://ncbi.nlm.nih.gov/pubmed/29180999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.01493
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