Nucleotide binding to ARL2 in the TBCD ARL2 β-tubulin complex drives conformational changes in β-tubulin

Microtubules are highly dynamic tubulin polymers that are required for a variety of cellular functions. Despite the importance of a cellular population of tubulin dimers, we have incomplete information about the mechanisms involved in the biogenesis of αβ-tubulin heterodimers. In addition to prefold...

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Udgivet i:J Mol Biol
Main Authors: Francis, Joshua W., Goswami, Devrishi, Novick, Scott J., Pascal, Bruce D., Weikum, Emily R., Ortlund, Eric A., Griffin, Patrick R., Kahn, Richard A.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5693757/
https://ncbi.nlm.nih.gov/pubmed/28970104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2017.09.016
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