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The muscle regulatory transcription factor MyoD participates with p53 to directly increase the expression of the pro-apoptotic Bcl2 family member PUMA

The muscle regulatory transcription factor MyoD is a master regulator of skeletal myoblast differentiation. We have previously reported that MyoD is also necessary for the elevated expression of the pro-apoptotic Bcl2 family member PUMA, and the ensuing apoptosis, that occurs in a subset of myoblast...

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Foilsithe in:Apoptosis
Main Authors: Harford, Terri J., Kliment, Greg, Shukla, Girish C., Weyman, Crystal M.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2017
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5693709/
https://ncbi.nlm.nih.gov/pubmed/28918507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10495-017-1423-x
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