A new model system identifies EGFR/HER2 and HER2/HER3 heterodimers as potent inducers of oesophageal epithelial cell invasion

Oesophageal squamous cell carcinomas and oesophageal adenocarcinomas display distinct patterns of ErbB expression and dimers. The functional effects of specific ErbB homo- or heterodimers on oesophageal (cancer) cell behaviour, particularly invasion of early carcinogenesis remains unknown. Here, a n...

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Detalhes bibliográficos
Publicado no:J Pathol
Main Authors: Fichter, Christiane Daniela, Przypadlo, Camilla Maria, Buck, Achim, Herbener, Nicola, Riedel, Bianca, Schäfer, Luisa, Nakagawa, Hiroshi, Walch, Axel, Reinheckel, Thomas, Werner, Martin, Lassmann, Silke
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5693673/
https://ncbi.nlm.nih.gov/pubmed/28940194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.4987
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