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Breast cancer complexity: Implications of intratumoral heterogeneity in clinical management

Generation of intratumoral phenotypic and genetic heterogeneity has been attributed to clonal evolution and cancer stem cells that together give rise to a tumor with complex ecosystems. Each ecosystem contains various tumor cell subpopulations and stromal entities, which depending upon their composi...

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Detalhes bibliográficos
Publicado no:Cancer Metastasis Rev
Main Authors: Haynes, Brittany, Sarma, Ashapurna, Nangia-Makker, Pratima, Shekhar, Malathy P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5693662/
https://ncbi.nlm.nih.gov/pubmed/28752247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10555-017-9684-y
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