L-arginine availability and arginase activity: Characterization of amino acid permease 3 in Leishmania amazonensis

BACKGROUND: Leishmania uses the amino acid L-arginine as a substrate for arginase, enzyme that produces urea and ornithine, last precursor of polyamine pathway. This pathway is used by the parasite to replicate and it is essential to establish the infection in the mammalian host. L-arginine is not s...

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Publicado en:PLoS Negl Trop Dis
Autores principales: Aoki, Juliana Ide, Muxel, Sandra Marcia, Zampieri, Ricardo Andrade, Acuña, Stephanie Maia, Fernandes, Juliane Cristina Ribeiro, Vanderlinde, Rubia Heloisa, Sales, Maria Carmen Oliveira de Pinho, Floeter-Winter, Lucile Maria
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5693463/
https://ncbi.nlm.nih.gov/pubmed/29073150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0006025
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