BORC regulates the axonal transport of synaptic vesicle precursors by activating ARL-8

Axonal transport of synaptic vesicle precursors (SVPs) is essential for synapse development and function. The conserved ARF-like small GTPase ARL-8 is localized to SVPs and directly activates UNC-104/KIF1A, the axonal-transport kinesin for SVPs in C. elegans. It is not clear how ARL-8 is activated i...

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Udgivet i:Curr Biol
Main Authors: Niwa, Shinsuke, Tao, Li, Lu, Sharon Y., Liew, Gerald M., Feng, Wei, Nachury, Maxence V., Shen, Kang
Format: Artigo
Sprog:Inglês
Udgivet: 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5693321/
https://ncbi.nlm.nih.gov/pubmed/28823680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2017.07.013
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