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Heterozygous deletion of both sclerostin (Sost) and connexin43 (Gja1) genes in mice is not sufficient to impair cortical bone modeling

Connexin43 (Cx43) is the main gap junction protein expressed in bone forming cells, where it modulates peak bone mass acquisition and cortical modeling. Genetic ablation of the Cx43 gene (Gja1) results in cortical expansion with accentuated periosteal bone formation associated with decreased express...

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Bibliografski detalji
Izdano u:PLoS One
Glavni autori: Grimston, Susan K., Fontana, Francesca, Watkins, Marcus, Civitelli, Roberto
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5693294/
https://ncbi.nlm.nih.gov/pubmed/29149200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0187980
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