VEGF-A and PDGF-B combination gene therapy prolongs angiogenic effects via recruitment of interstitial mononuclear cells and paracrine effects rather than improved pericyte coverage of angiogenic vessels

Vessel stabilisation and the inhibition of side-effects such as tissue edema are essential in angiogenic gene therapy. Thus, combination gene transfers (GT) stimulating both endothelial cell and pericyte proliferation have become of interest. However, there is currently little data to support combin...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Circ Res
Egile Nagusiak: Korpisalo, Petra, Karvinen, Henna, Rissanen, Tuomas T., Kilpijoki, Johanna, Marjomäki, Varpu, Baluk, Peter, McDonald, Donald M., Cao, Yihai, Eriksson, Ulf, Alitalo, Kari, Ylä-Herttuala, Seppo
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2008
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5693290/
https://ncbi.nlm.nih.gov/pubmed/18832750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.108.182287
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