VEGF-A and PDGF-B combination gene therapy prolongs angiogenic effects via recruitment of interstitial mononuclear cells and paracrine effects rather than improved pericyte coverage of angiogenic vessels

Vessel stabilisation and the inhibition of side-effects such as tissue edema are essential in angiogenic gene therapy. Thus, combination gene transfers (GT) stimulating both endothelial cell and pericyte proliferation have become of interest. However, there is currently little data to support combin...

Full description

Saved in:
Bibliographic Details
Published in:Circ Res
Main Authors: Korpisalo, Petra, Karvinen, Henna, Rissanen, Tuomas T., Kilpijoki, Johanna, Marjomäki, Varpu, Baluk, Peter, McDonald, Donald M., Cao, Yihai, Eriksson, Ulf, Alitalo, Kari, Ylä-Herttuala, Seppo
Format: Artigo
Language:Inglês
Published: 2008
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5693290/
https://ncbi.nlm.nih.gov/pubmed/18832750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.108.182287
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items