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Local protein kinase A action proceeds through intact holoenzymes

Hormones can transmit signals through adenosine 3′,5′-monophosphate (cAMP) to precise intracellular locations. The fidelity of these responses relies on the activation of localized protein kinase A (PKA) holoenzymes. Association of PKA regulatory type II (RII) subunits with A-kinase—anchoring protei...

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Foilsithe in:Science
Main Authors: Smith, F. Donelson, Esseltine, Jessica L., Nygren, Patrick J., Veesler, David, Byrne, Dominic P., Vonderach, Matthias, Strashnov, Ilya, Eyers, Claire E., Eyers, Patrick A., Langeberg, Lorene K., Scott, John D.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2017
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5693252/
https://ncbi.nlm.nih.gov/pubmed/28642438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aaj1669
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