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GENE-42. MOLECULAR AND HISTOLOGIC FEATURES OF A SERIES OF SPORADIC AND FAMILIAL SCHWANNOMAS

Schwannomas are found either sporadically or as part of a syndrome. Genetic alterations found in schwannomas include those in NF2 and SMARCB1 (implicated in schwannomatosis), and BRAF V600E. Reduced copy number of chromosome 22q can be the mechanism for loss of the unaltered allele ofNF2 and/orSMARC...

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Bibliografiske detaljer
Udgivet i:Neuro Oncol
Main Authors: Williams, Erik, Kim, James, Muzikansky, Alona, Shaw, McKenzie, Iafrate, A John, Plotkin, Scott, Suva, Mario, Stemmer-Rachamimov, Anat
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5693167/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.415
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