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STEM-18. RENIN-ANGIOTENSIN SYSTEM IDENTIFIED BY PHAGE DISPLAY SCREENING IS A NEW THERAPEUTIC TARGET FOR GLIOBLASTOMA AND REGULATES PROLIFERATION OF GLIOBLASTOMA STEM CELLS

Glioblastoma stem cells (GSCs) are tumor-initiating cells and contribute to chemo-radiation resistance of glioblastoma multiforme (GBM) with poor prognosis. Cell-cell interactions in GBM niche regulate and maintain GSCs leading to tumor progression. Secretory molecules from different cell types in G...

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Veröffentlicht in:Neuro Oncol
Hauptverfasser: Kim, Jongmyung (John), Xie, Qi, Rich, Jeremy, Liu, James
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5693162/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.934
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