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Therapeutic Targeting of Cancer Stem Cells in Human Glioblastoma by Manipulating the Renin-Angiotensin System

Patients with glioblastoma (GB), a highly aggressive brain tumor, have a median survival of 14.6 months following neurosurgical resection and adjuvant chemoradiotherapy. Quiescent GB cancer stem cells (CSCs) invariably cause local recurrence. These GB CSCs can be identified by embryonic stem cell ma...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Tan, David C. H., Roth, Imogen M., Wickremesekera, Agadha C., Davis, Paul F., Kaye, Andrew H., Mantamadiotis, Theo, Stylli, Stanley S., Tan, Swee T.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6912312/
https://ncbi.nlm.nih.gov/pubmed/31683669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells8111364
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