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TMOD-28. INTERLEUKIN-13 TARGETED PSEUDOMONAS TOXIN TREATMENT OF MALIGNANT PERIPHERAL NERVE SHEATH TUMORS
Malignant peripheral nerve sheath tumors (MPNSTs) are soft tissue sarcomas that arise from peripheral nerves. A target of MPNSTs is the receptor for interleukin-13 (IL-13R). IL-13R has an α1 and α2 subtype, and activation of α1 leads to caspase-3 mediated apoptosis. MPNSTs have increased expression...
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| Gepubliceerd in: | Neuro Oncol |
|---|---|
| Hoofdauteurs: | , , , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Oxford University Press
2017
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5693091/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.1065 |
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