EXTH-44. ADDITION OF THE CARBONIC ANHYDRASE IX INHIBITOR SLC-0111 TO TEMOZOLOMIDE EXTENDS SURVIVAL OF MICE BEARING ORTHOTOPIC GLIOBLASTOMAS

Brain tumor microenvironments characterized by hypoxia, restricted glucose, and acidic stress contain a subset of neoplastic cells that thrive in these environments, identified as brain tumor initiating cells (BTICs). BTICs are resistant to chemo- and radiotherapy, providing a reservoir for tumor re...

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Publicat a:Neuro Oncol
Autors principals: Boyd, Nathaniel, Walker, Kiera, Tran, Anh, Hackney, James, McDonald, Paul, Benavides, Gloria, Bevensee, Mark, Gillespie, Yancey, Nabors, Burt, Darley-Usmar, Victor, Dedhar, Shoukat, Hjelmeland, Anita
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2017
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Abstracts
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5693064/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.336
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