PDTM-35. THERAPEUTIC RELEVANCE OF YAP/TAZ ACTIVITY IN PEDIATRIC HIGH-GRADE GLIOMA.

High-grade gliomas (HGGs), including glioblastoma (GBM) and diffuse intrinsic pontine glioma (DIPG), are the most aggressive malignant high-grade gliomas in children, and are incurable with current therapies. The most frequent genetic lesions that drive formation of HGGs include amplification/overex...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Oh, Se-Yeong, Vigneswaran, Krishanthan, Schniederjan, Matthew, Horbinski, Craig, Hambardzumyan, Dolores, Becher, Oren, Kenney, Anna, Read, Renee
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
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Abstracts
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5692953/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.798
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