CSIG-31. PRE-CLINICAL STUDY AND CLINICAL DEVELOPMENT OF AXL-TARGETING THERAPY FOR RECURRENT GLIOBLASTOMA

Glioblastoma (GBM) is a lethal disease without effective therapies. Previously we reported that the TAM receptor tyrosine kinase family member AXL is upregulated in mesenchymal GBM and its knockdown induces apoptosis of mesenchymal but not proneural glioma sphere cultures (GSCs). In this study, we r...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Neuro Oncol
Main Authors: Sadahiro, Hirokazu, Kang, Kyung-Don, Nabors, Burt, Norian, Lyse, Hambardzumyan, Dolores, Dasgupta, Biplab, Nakada, Mitsutoshi, Nakano, Ichiro
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2017
Teme:
Abstracts
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5692918/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.225
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki