CSIG-31. PRE-CLINICAL STUDY AND CLINICAL DEVELOPMENT OF AXL-TARGETING THERAPY FOR RECURRENT GLIOBLASTOMA

Glioblastoma (GBM) is a lethal disease without effective therapies. Previously we reported that the TAM receptor tyrosine kinase family member AXL is upregulated in mesenchymal GBM and its knockdown induces apoptosis of mesenchymal but not proneural glioma sphere cultures (GSCs). In this study, we r...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Sadahiro, Hirokazu, Kang, Kyung-Don, Nabors, Burt, Norian, Lyse, Hambardzumyan, Dolores, Dasgupta, Biplab, Nakada, Mitsutoshi, Nakano, Ichiro
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5692918/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.225
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