EXTH-81. ACNU AS THE BEST NITROSOUREA FOR LOCAL CONVECTION-ENHANCED DELIVERY: REPORT ON PHARMACOKINETICS

BACKGROUND: Nitrosourea represents one of the effective chemotherapeutic agents against gliomas. Among clinically available Nitrosoureas; ACNU/BCNU/CCNU/MCNU, ACNU is the most hydrophilic agent. We have demonstrated that hydrophilic agents achieve robust tissue distribution when delivered locally wi...

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Pubblicato in:Neuro Oncol
Autori principali: Saito, Ryuta, Wenting, Jia, Sato, Aya, Okuno, Saori, Nakamura, Taigen, Chonan, Masashi, Zhang, Rong, Kanamori, Masayuki, Tominaga, Teiji
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2017
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Abstracts
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5692883/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.371
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