TMOD-39. IDENTIFICATION OF EFFICACIOUS AGENTS IN PEDIATRIC EPENDYMOMA THROUGH HIGH-THROUGHPUT DRUG SCREENING IN MATCHING PAIRS OF PATIENT DERIVED ORTHOTOPIC XENOGRAFT (PDOX) NEUROSPHERE AND MONOLAYER CELLS

OBJECTIVE: Ependymoma (EPN) is one of the most malignant tumors and recurrence occurs in almost 50% of patients. Recent transcriptional and copy number profiling of EPN has identified few driver genes and pointed to a balanced genomic profile. Since existing and emerging evidence implicating the epe...

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Bibliografiske detaljer
Udgivet i:Neuro Oncol
Main Authors: Guo, Lei, Zhang, Huiyuan, Zhao, Sibo, Du, Yuchen, Qi, Lin, Bae, Goeun, Braun, Frank, Kogiso, Mari, Lindsay, Holly, Injac, Sarah, Baxter, Patricia, Su, Jack, Stephan, Clifford, Davies, Peter, Li, Xiao-Nan
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2017
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Abstracts
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5692790/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.1075
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