SCDT-38. SAFETY AND EFFICACY OF INTRAVENTRICULAR (131)I-LABELED MONOCLONAL ANTIBODY 8H9 TARGETING THE SURFACE GLYCOPROTEIN B7-H3 IN PATIENTS WITH CNS/LM DISEASE

Tumors metastasizing to the central nervous system (CNS) are associated with significant mortality. We tested the toxicity and dosimetry of intraventricular (131)I-labeled monoclonal antibody 8H9 targeting surface glycoprotein B7-H3 in patients with CNS. Tumor B7-H3 expression was assessed by immuno...

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Publicado en:Neuro Oncol
Autores principales: Kramer, Kim, Kushner, Brian, Modak, Shakeel, Pandit-Taskar, Neeta, Tomlinson, Ursula, Donzelli, Maria, Wolden, Suzanne, Zanzonico, Pat, Humm, John, Haque, Sophia, Souweidane, Mark, Greenfield, Jeffrey, Basu, Ellen, Roberts, Stephen, Carrasquillo, Jorge, Lewis, Jason, Lyashchenko, Serge, Larson, Steven, Cheung, Nai-Kong
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5692713/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.1119
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