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DDIS-05. DEVELOPMENT OF AN INHIBITOR AGAINST MUSASHI-1 AND ITS USE IN BRAIN TUMOR THERAPY
We identified the RNA binding protein Musashi1 (Msi1) as a major driver of glioblastoma and medulloblastoma. High Msi1 expression is prevalent in high-risk groups and correlates with poor prognosis. Biological and genomic analyses determined that Msi1 affects numerous cancer relevant processes and i...
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Publicado no: | Neuro Oncol |
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Autor principal: | |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Oxford University Press
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5692648/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.241 |
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