EXTH-50. DEVELOPMENT OF INVESTIGATOR INITIATED CLINICAL TRIAL OF TERT-TARGETING THERAPY USING ERIBULIN MESYLATE IN PATIENTS WITH RECURRENT GLIOBLASTOMA

Despite of recent intense investigations, no effective molecular targeting therapy has been successfully developed in patients with glioblastomas (GBMs). Approximately 60–80% of GBM harbor mutations in the promoter region of telomerase reverse transcriptase (TERT), which leads to its upregulation. I...

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Bibliografiske detaljer
Udgivet i:Neuro Oncol
Main Authors: Takahashi, Masamichi, Miki, Shunichiro, Fukuoka, Kohei, Maida, Yoshiko, Hayashi, Mitsuhiro, Hamada, Akinobu, Nishikawa, Ryo, Nagane, Motoo, Maruyama, Takashi, Mukasa, Akitake, Arakawa, Yoshiki, Arita, Hideyuki, Kitamura, Natsuko, Yonemori, Kan, Tamura, Kenji, Masutomi, Kenkichi, Narita, Yoshitaka, Ichimura, Koichi
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2017
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Abstracts
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5692632/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.342
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