ATIM-03. BIOMARKER ANALYSIS SUPPORTS THE VB-111 DUAL MECHANISM OF ACTION

BACKGROUND: VB-111 (Ofranergene Obadenovec) is non-integrating, non-replicating, Adeno 5 vector which targets the vasculature through induction of endothelial apoptosis. Our prior phase 2 study has shown a nearly doubling of overall survival (OS) in recurrent glioblastoma (rGBM) (59v32 weeks), and o...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Neuro Oncol
Prif Awduron: Gruslova, Aleksandra, Liu, Yichu, Wen, Patrick, Peters, Katherine B, Vredenburgh, James, Bokstein, Felix, Blumenthal, Deborah T, Cohen, Yael, Mendel, Itzhak, Breitbart, Eyal, Brenner, Andrew
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2017
Pynciau:
Abstracts
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5692628/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.100
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