EXTH-48. THE KETONE BODY β-HYDROXYBUTYRATE CHEMO- AND RADIO-SENSITIZES MALIGNANT GLIOMA CELLS BY INHIBITING HISTONE DEACETYLASE ACTIVITY AND DOWNREGULATING EXPRESSION OF RAD51

Mounting evidence suggests that raising blood ketones and reducing blood glucose may be an effect anti-glioma strategy. We have demonstrated that this approach not only impacts multiple hubs of glioma growth but also greatly increases survival in a mouse model of malignant glioma when administered i...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Woolf, Eric C, Bhattacharya, Aditi, Rossi, Alex P, Davidson, Makena M, Syed, Nelofer, Scheck, Adrienne C
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Abstracts
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5692626/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.340
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados