Quantitative proteomics identifies STEAP4 as a critical regulator of mitochondrial dysfunction linking inflammation and colon cancer

Inflammatory bowel disease (IBD) is a chronic inflammatory disorder and is a major risk factor for colorectal cancer (CRC). Hypoxia is a feature of IBD and modulates cellular and mitochondrial metabolism. However, the role of hypoxic metabolism in IBD is unclear. Because mitochondrial dysfunction is...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Xue, Xiang, Bredell, Bryce X., Anderson, Erik R., Martin, Angelical, Mays, Christopher, Nagao-Kitamoto, Hiroko, Huang, Sha, Győrffy, Balázs, Greenson, Joel K., Hardiman, Karin, Spence, Jason R., Kamada, Nobuhiko, Shah, Yatrik M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5692584/
https://ncbi.nlm.nih.gov/pubmed/29078383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1712946114
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados