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A unique surface on Pat1 C-terminal domain directly interacts with Dcp2 decapping enzyme and Xrn1 5′–3′ mRNA exonuclease in yeast

The Pat1 protein is a central player of eukaryotic mRNA decay that has also been implicated in translational control. It is commonly considered a central platform responsible for the recruitment of several RNA decay factors. We demonstrate here that a yeast-specific C-terminal region from Pat1 inter...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Charenton, Clément, Gaudon-Plesse, Claudine, Fourati, Zaineb, Taverniti, Valerio, Back, Régis, Kolesnikova, Olga, Séraphin, Bertrand, Graille, Marc
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5692570/
https://ncbi.nlm.nih.gov/pubmed/29078363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1711680114
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