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CSIG-34. PDGFRb SIGNALING MAINTAINS GLIOBLASTOMA SURVIVAL VIA HYPOXIA-INDUCED MITOPHAGY

INTRODUCTION: Platelet-derived growth factor (PDGF) signaling plays a key role in gliomagenesis. Glioblastomas express all PDGF ligands, and both cell membrane receptors, PDGFRα and PDGFRβ, that are involved in pro-survival autocrine and paracrine loops. Our previous work demonstrated that expressio...

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書目詳細資料
發表在:Neuro Oncol
Main Authors: Jung, Jinkyu, Gilbert, Mark R, Park, Deric M
格式: Artigo
語言:Inglês
出版: Oxford University Press 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5692492/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.228
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