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CSIG-40. PHOSPHOGLYCERATE MUTASE 1 (PGAM1) ACTIVATES DNA DAMAGE REPAIR VIA REGULATION OF WIP1 ACTIVITY
In normal cells, phosphoglycerate mutase 1(PGAM1) converts 3-phospho glycerate to 2-phospho glycerate. PGAM1, however is overexpressed in different forms of cancer and has been suggested to have additional functions beyond its role in metabolism. We here report that PGAM1 is overexpressed in GBMs an...
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| Veröffentlicht in: | Neuro Oncol |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5692483/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.234 |
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