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CSIG-40. PHOSPHOGLYCERATE MUTASE 1 (PGAM1) ACTIVATES DNA DAMAGE REPAIR VIA REGULATION OF WIP1 ACTIVITY

In normal cells, phosphoglycerate mutase 1(PGAM1) converts 3-phospho glycerate to 2-phospho glycerate. PGAM1, however is overexpressed in different forms of cancer and has been suggested to have additional functions beyond its role in metabolism. We here report that PGAM1 is overexpressed in GBMs an...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Neuro Oncol
Prif Awduron: Mukherjee, Joydeep, Ohba, Shigeo, Johannessen, Tor-Christian Aase, Kamalakar, Chatla, Pieper, Russell O
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5692483/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.234
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