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CSIG-40. PHOSPHOGLYCERATE MUTASE 1 (PGAM1) ACTIVATES DNA DAMAGE REPAIR VIA REGULATION OF WIP1 ACTIVITY

In normal cells, phosphoglycerate mutase 1(PGAM1) converts 3-phospho glycerate to 2-phospho glycerate. PGAM1, however is overexpressed in different forms of cancer and has been suggested to have additional functions beyond its role in metabolism. We here report that PGAM1 is overexpressed in GBMs an...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Mukherjee, Joydeep, Ohba, Shigeo, Johannessen, Tor-Christian Aase, Kamalakar, Chatla, Pieper, Russell O
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5692483/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.234
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