SCDT-06. QUANTIFIABLE LEVELS OF THE TRANSGENE, CYTOSINE DEAMINASE, IN TUMOR SAMPLES FOLLOWING INTRAVENOUS DELIVERY OF TOCA 511 IN PATIENTS WITH RECURRENT HIGH GRADE GLIOMA

Toca 511 (vocimagene amiretroprepvec) is an investigational, conditionally lytic, retroviral replicating vector that encodes an optimized yeast cytosine deaminase (CD) gene. The CD gene converts the prodrug, Toca FC (investigational, extended-release 5-fluorocytosine), into the chemotherapeutic, 5-F...

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Detaylı Bibliyografya
Yayımlandı:Neuro Oncol
Asıl Yazarlar: Walbert, Tobias, Bota, Danilella, Vogelbaum, Michael, Kalkanis, Steven, Liau, Linda, Mikkelsen, Tom, Gruber, Harry, Shorr, Jolene, Rodriguez-Aguirre, Maria, Ostertag, Derek, Mitchell, Leah, Jolly, Doug, Cloughesy, Timothy
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2017
Konular:
Abstracts
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5692436/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.1089
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