NIMG-28. INCREASED MUTATION BURDEN (HYPERMUTATION) IN GLIOMAS IS ASSOCIATED WITH A UNIQUE RADIOMIC TEXTURE SIGNATURE IN MAGNETIC RESONANCE IMAGING

INTRODUCTION: Increased mutation burden (hypermutation) has been reported in low and high-grade gliomas. Hypermutation is typically due to failure of DNA repair machinery such as mismatch repair (MMR) or disruption of DNA fidelity due to mutations in DNA polymerase genes (POLE and POLD). The inciden...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Neuro Oncol
Päätekijät: Hassan, Islam, Kotrotsou, Aikaterini, Matsuoka, Carlos Kamiya, Alfaro-Munoz, Kristin, Elshafeey, Nabil, Zinn, Pascal, de Groot, John, Colen, Rivka
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2017
Aiheet:
Abstracts
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5692419/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.603
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia