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NIMG-28. INCREASED MUTATION BURDEN (HYPERMUTATION) IN GLIOMAS IS ASSOCIATED WITH A UNIQUE RADIOMIC TEXTURE SIGNATURE IN MAGNETIC RESONANCE IMAGING
INTRODUCTION: Increased mutation burden (hypermutation) has been reported in low and high-grade gliomas. Hypermutation is typically due to failure of DNA repair machinery such as mismatch repair (MMR) or disruption of DNA fidelity due to mutations in DNA polymerase genes (POLE and POLD). The inciden...
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| Publicado no: | Neuro Oncol |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5692419/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.603 |
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