SCDT-43. BLOCKING OF INTERACTING CK2 AND EGFR PATHWAYS BY TUMOR-TARGETING NANOCONJUGATES INCREASES THERAPEUTIC EFFICACY AGAINST GLIOBLASTOMA MULTIFORME

Glioblastoma multiforme (GBM) remains the deadliest brain tumor in adults. To inhibit GBMs more effectively, polymalic acid-based blood-brain barrier (BBB) crossing nanobioconjugates were synthesized that are delivered to the cytoplasm of cancer cells and specifically inhibit the master regulator se...

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Publicado en:Neuro Oncol
Main Authors: Black, Keith, Patil, Rameshwar, Ding, Hui, Ljubimov, Vladimir, Shatalova, Ekaterina, Holler, Eggehard, Ljubimova, Julia
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2017
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Abstracts
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5692312/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.1123
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