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SCDT-43. BLOCKING OF INTERACTING CK2 AND EGFR PATHWAYS BY TUMOR-TARGETING NANOCONJUGATES INCREASES THERAPEUTIC EFFICACY AGAINST GLIOBLASTOMA MULTIFORME
Glioblastoma multiforme (GBM) remains the deadliest brain tumor in adults. To inhibit GBMs more effectively, polymalic acid-based blood-brain barrier (BBB) crossing nanobioconjugates were synthesized that are delivered to the cytoplasm of cancer cells and specifically inhibit the master regulator se...
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| Udgivet i: | Neuro Oncol |
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| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5692312/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.1123 |
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